Thursday, 4 April 2019

Labeling proteins with ubiquitin paves new road to cell regulation research

Human cells have a sophisticated regulatory system that consists of labeling proteins with the small molecule ubiquitin. In a first, a team from the Technical University of Munich (TUM) has succeeded in marking proteins with ubiquitin in a targeted manner in test tubes as well as in living cells. The procedure opens the door to exploring the inner workings of this vital regulatory system.

* This article was originally published here

Scientists outline the promises and pitfalls of machine learning in medicine

A 49-year-old man notices a painless rash on his shoulder but doesn't seek care. Months later, during a routine physical, his doctor notices the rash and diagnoses it as a benign skin condition. More time passes, and during a routine screening test, a nurse points out the rash to another physician who urges the patient to see a dermatologist. A dermatologist performs a biopsy of it. The pathology report reveals a noncancerous lesion. The dermatologist seeks a second reading of the pathology slides. This time, a drastically different verdict: invasive melanoma. The patient is immediately started on chemotherapy. Weeks later, a physician friend asks him why he's not on immunotherapy instead.

* This article was originally published here

People with autism have an altered sense of self

New research has indicated that people with autism have an altered sense of self, which may explain some of the differences shown in social functioning.

* This article was originally published here

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