Friedreich's ataxia (FRDA) is a rare, inherited disorder that causes progressive damage to the nervous system. This damage leads to ataxia—problems with movement and coordination—that worsens with time. Other symptoms, such as loss of strength and sensation in the arms and legs, muscle stiffness, and impaired speech, hearing, and vision, can also result. New research in cell models and in mice suggests that limited environmental oxygen, known as hypoxia, might one day help FRDA patients, although the safety of doing so is yet unknown.
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